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The metal binds to the MRE-binding protein, which in turn initiates increased transcription of the growth hormone gene. This technology could be applied to ...
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Members of the ArsR/SmtB family of metalloregulatory proteins possess a highly conserved DNA recognition helix-turn-helix domain and bind as homodimers to their ...
Metal Binding Protein|Dna Binding Protein|Regulator|Gene Regulation from www.jbc.org
Dec 19, 2019 · The response to cognate metal binding includes residues right at the N terminus of the protein. (83, 85), unlike CsoR, suggesting a variation on ...
Metal Binding Protein|Dna Binding Protein|Regulator|Gene Regulation from www.mdpi.com
Metal ions play three fundamental roles in proteins: structural, regulatory, and enzymatic. The binding of some metal ions stabilize proteins or protein domains ...
In this context, allosteric regulation is the process by which metal binding to specific sites on the protein influences DNA binding by a distant region. Metal ...
Metal Binding Protein|Dna Binding Protein|Regulator|Gene Regulation from www.nature.com
May 8, 2018 · Ferric uptake regulators (Fur) are a family of transcription factors coupling gene regulatory events to metal concentration.
A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA ...
The MerR protein mediates the induction of the mercury resistance phenotype in bacteria; it has been isolated in order to study the effects of metal-ion ...
Metal Binding Protein|Dna Binding Protein|Regulator|Gene Regulation from www.nature.com
Oct 24, 2019 · Metal-binding by a secreted protein could decrease the metal available in the external medium thereby decreasing the intracellular bacterial ...
Metal Binding Protein|Dna Binding Protein|Regulator|Gene Regulation from www.sciencedirect.com
These small proteins with a high content of cysteines can bind and thereby sequester heavy metals. Metallothioneins were discovered in 1957 by Margoshes and ...